BrightMEM^™ Corneal Allografts

Exciting News!

Lions World Vision Institute offers BrightMEM^™ Corneal Allografts provided by BrightSTAR Therapeutics.

Ocular Surface Reconstruction with BrightMEM Corneal Allografts – A Foundation for Durable Epithelial Regeneration

BrightMEM is a novel corneal allograft that promotes regeneration of the corneal epithelium. It is made from Descemet’s Membrane, which creates a new foundation for the ocular surface, capable of supporting native limbal epithelial stem cells. This represents a new treatment for patients with impaired corneal healing.

BrightMEM is aseptically processed from tissues obtained from donated human tissue (corneas) according to the current Good Tissue Practices(cGTP) regulations established by the US Food & Drug Administration (FDA).

BrightMEM expresses proteins that stimulate limbal stem cell growth while resisting degradation. In preclinical studies, BrightMEM supported limbal stem cell expansion and maintained a population of stem cells in the basal corneal epithelium. Clinically, up to this point, there have been no instances where the corneal epithelium failed to regenerate when treated with BrightMEM.

BrightMEM offers hope as a durable solution for patients with severe corneal disorders through its regenerative properties.

Advantages of BrightMEM?

• Promotes corneal epithelial regeneration, optimizes limbal stem cell growth
• Optically clear
• More durable and resistant to degradation than alternatives
• Preclinical data shows limbal stem cell and epithelium support and protection from stromal melting
• Early clinical data shows epithelialization without any serious tissue related adverse reactions

Learn more about BrightMEM